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15 Day itinerary in Argentina, South America

Patagonia Argentina & Chile: Highlights Exploration

Embark on a comprehensive journey across the wonders of Patagonia with this expertly curated Argentina and Chile itinerary. Start in Buenos Aires, the vibrant birthplace of tango, before flying south to Ushuaia at the edge of the world. Explore Tierra del Fuego, marvel at glaciers in El Calafate, cr... Read More

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Maria ConstanceQwerty Travel Argentina

By Maria Constance and Qwerty Travel Argentina

Overview

Physical Difficulty

Light
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Recommended Age

Minimum 2

Maximum 85

Operated in

English, Spanish

GUIDANCE

On Some Day Trips

starting point

Buenos Aires

trip type

Private

trip attributes

Nature & Widlife

Patagonia Adventures

Eco

Hiking

Cultural

Adventure

Landscapes & Sceneries

Day Trips & Excursions

Photography

Meet local people

Multi-Country

Purposeful Travel

Water & Coastline

Nature & Wildlife

Start/End

Night

Highlights

1

Sail the Andean Lake Crossing from Puerto Varas to Bariloche

2

Experience Torres del Paine National Park’s granite spires and lakes

3

Witness the majesty of Perito Moreno Glacier

4

Explore Patagonia’s best—from Buenos Aires to Ushuaia to Bariloche

Itinerary

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Day 1

place Welcome to Buenos Aires: The Gateway to Argentina

Arrive at Buenos Aires International Airport and transfer to the ibis Buenos Aires Obelisco hotel. Check in from 2:00 PM. The rest of your day is free to unwind or dive into the city’s lively streets. 


Buenos Aires is renowned for its classic architecture and as the cradle of tango, blending European grandeur and Latin rhythm at every turn.


Accommodation:

  • Mid-Range: ibis Buenos Aires Obelisco
Day 2

place Discover Buenos Aires’ Multifaceted Charm

Spend the morning exploring Buenos Aires, a city bursting with energy and diversity. Visit its emblematic Obelisk and stroll through famous plazas like Plaza de Mayo, Plaza San Martín, and Plaza Congreso. Wind through major avenues—Corrientes, Mayo, and the grand 9 de Julio—and past historical districts such as La Boca, San Telmo, and Montserrat. Traverse elegant Palermo, Recoleta, and vibrant Puerto Madero; view city parks including Lezama and Tres de Febrero, and pass by financial districts and a football stadium. The afternoon is yours for further adventures or relaxation. 


The city’s Recoleta Cemetery is one of the most visited cultural sites in Latin America.


Guide: Included for the day

Meals: Breakfast

Accommodation:

  • Mid-Range: ibis Buenos Aires Obelisco
Day 3

place Buenos Aires to Ushuaia: Journey to the End of the World

Transfer from your hotel to the airport for your flight to Ushuaia, perched where the Andes meet the Beagle Channel. Upon arrival, head to your accommodation. 


Ushuaia is celebrated as the world’s southernmost city, surrounded by rugged landscapes that drew explorers like Darwin.


Meals: Breakfast

Accommodation:

  • Mid-Range: Patagonia Jarke
Day 4

place Tierra del Fuego National Park Exploration

Start your day with a pick up at your hotel to experience one of Ushuaia’s most awe-inspiring adventures: Tierra del Fuego National Park. Just 12 km from the city center, this is where you reach the true End of the World and feel the magic of being in a place unlike any other. Before entering the park, you’ll pause at the End of the World train station. Here, you may choose to board the legendary narrow-gauge train (optional, about 60 minutes) which winds through sub-Antarctic forest and ends inside the National Park; if not, enjoy a walk in the pristine Fuegian forest (note: the walk may be cancelled in winter depending on weather). After the train or walk, the group reunites within the park and continues by vehicle and guide to Ensenada Bay, a remarkable spot where the Andes, sub-Antarctic forest, and sea meet to form an ecosystem unique in Argentina. In this area, you’ll trace the legacy of the native inhabitants through preserved archaeological remains and discover the last post office in America—sometimes open so you can send a postcard from this unforgettable location (Ensenada Bay is closed in winter). The journey continues to several scenic lookouts for short walks and opportunities to photograph the park’s diverse flora and fauna. Next, stop by Acigami Glacier Lake (also known as Roca Lake), a transboundary lake shared with Chile, and finally, reach Lapataia Bay, where you’ll see the iconic sign marking the southern terminus of the Pan-American Highway after more than 15,000 kilometers from Alaska. In clear weather, Antarctica lies just 1,000 km south.


Tierra del Fuego National Park is also a protected haven for rare local species and is deeply tied to the indigenous Yámana people, whose age-old presence is part of the land’s story.


Guide: Included for the day

Meals: Breakfast

Accommodation:

  • Mid-Range: Patagonia Jarke
Day 5

place Ushuaia to El Calafate: Enter Glacier Country

Transfer to Ushuaia airport and catch your flight to El Calafate. Once you land, transfer into town and check in at Michelangelo Hotel Calafate. 


El Calafate sits beside Lake Argentino, gateway to massive glaciers and Patagonian steppe.


Meals: Breakfast

Accommodation:

  • Mid-Range: Michelangelo Hotel Calafate
Day 6

place Perito Moreno Glacier Adventure & Nautical Safari

Depart from El Calafate for a full day at the iconic Perito Moreno Glacier. Travel 80 km to panoramic viewpoints and walkways, wandering among ramps and balconies at different heights for superfine perspectives of the advancing ice. Embark on a 1-hour boat ride, gliding within 150 meters of Perito Moreno’s towering face. Witness its thunderous calving and shifting blue hues before returning to El Calafate. 


The Perito Moreno Glacier is known for its rare status as an advancing glacier and its dramatic, frequent ice break-offs.


Guide: Included for the day

Meals: Breakfast

Accommodation:

  • Mid-Range: Michelangelo Hotel Calafate
Day 7

place El Calafate: Free Day to Explore

Today is yours to enjoy El Calafate at your own pace. Take time to stroll through town, opt for more glacier excursions by boat, or immerse yourself in Patagonian gaucho culture with a ranch visit that showcases traditional skills and lifestyles. 


El Calafate has blossomed from a modest sheep-farming village into a thriving Patagonian adventure hub on the shores of Lake Argentino.


Meals: Breakfast

Accommodation:

  • Mid-Range: Michelangelo Hotel Calafate
Day 8

place El Calafate to Puerto Natales: Gateway to Chilean Patagonia

After breakfast, transfer to El Calafate’s bus station and board the regular bus to Puerto Natales, crossing into Chile. Upon arrival, a local team member will greet you and transfer you to your hotel. The rest of the day is at your leisure to begin discovering this bustling Patagonian town. 


Puerto Natales serves as the main entry point for some of Chile’s most famous national parks.


Meals: Breakfast

Accommodation:

  • Mid-Range: If Patagonia Hotel
Day 9

place Torres del Paine National Park Discovery

Begin with a visit to the Cueva del Milodón, a grand cavern 200 meters long, 30 meters high, and 80 meters wide, famed for preserving fresh skin and bones of the prehistoric giant sloth, the mylodon. After a half-hour inside the cave, continue to Cerro Castillo for a refreshment break, then head towards Torres del Paine through a changing landscape of steppe and forest. Spot local wildlife such as the rhea (South American ostrich) and guanaco grazing freely. Inside the park, discover turquoise lagoons, ice-capped mountains, and varied fauna. Pause for a 15-minute walk to the Salto Grande waterfall on the Paine River. After lunch, travel to Lake Grey for a walk to its pebble beach and distant views of the Grey Glacier. Return to Puerto Natales via the scenic route that may border Toro, Porteño, and Sofía lakes. 


Remnants of the mylodon were found in 1895, sparking a wave of paleontological interest.


Guide: Included for the day

Meals: Breakfast

Accommodation:

  • Mid-Range: If Patagonia Hotel
Day 10

place Puerto Natales to Puerto Varas: Reaching Lakes Country

Early in the morning, transfer by bus to Punta Arenas airport, with a pause at Punta Arenas bus station. Fly to Puerto Montt and, upon arrival, transfer to your hotel in Puerto Varas with the day at leisure. 


Puerto Varas is renowned for its beautiful setting along Lake Llanquihue, with snowcapped Osorno Volcano in the distance.


Meals: Breakfast

Accommodation:

  • Mid-Range: Hotel Boutique Casa Kalfu
Day 11

place Puerto Varas to Bariloche: The Legendary Lake Crossing

Today you embark on the legendary Andean Lake Crossing, starting from Puerto Varas in Chile and ending in Bariloche, Argentina. This international journey is an adventure across the Andes Mountains, gliding through three stunning lakes—Todos los Santos, Frías, and Nahuel Huapi—each offering magical views of untouched Patagonian landscapes. The route also includes four scenic land stretches connecting the lakes, making it a truly unique way to traverse this wild border region. Along the way, admire dramatic mountain backdrops and landscapes shaped by glaciers that left their marks thousands of years ago. What started as a commercial trade route has become one of Patagonia’s top travel experiences, with 180 kilometers navigated annually by over 30,000 travelers. Passing through virgin forests, across vivid blue waters, and between snowcapped peaks, you’ll understand why the Lake Crossing is considered an unforgettable adventure. Upon arrival in Bariloche, settle into your hotel and start to take in the Swiss-like scenery of this Andean town. 


This crossing follows a path rich in the stories of explorers and traders who once linked these isolated communities by water.


Guide: Included for the day

Meals: Breakfast

Accommodation:

  • Mid-Range: Hotel Carlos V Patagonia Bariloche.
Day 12

place Bariloche Small Circuit & Campanario Hill: Scenic Marvels

Today you’ll enjoy a unique tour around San Carlos de Bariloche, winding through its forests, lakes, and mountains along the famous Avenida Bustillo beside Lake Nahuel Huapi. The picturesque landscape is ever-present as you travel, with natural viewpoints like Bahía López and Punto Panorámico offering ideal spots to soak in the marvels of the region. After passing Playa Bonita, you’ll reach the foot of Cerro Campanario, where you ascend to the 1,050-meter summit. At the top, a cross commemorates the first mass celebrated by Monsignor De Andrea on February 2, 1930. The hill’s charming café and two open terraces provide some of the most breathtaking and fascinating views in the area. They reveal lakes such as Nahuel Huapi and Perito Moreno, the El Trébol lagoon, the San Pedro Peninsula, Llao Llao, Victoria Island, and a panorama of surrounding peaks including the Otto, López, Goye, Cathedral, and Chapel mountains. The chairlift—built with cutting-edge Doppelmayer technology—offers safe, five to seven-minute rides at a variable speed of 1.3 meters per second, with eight towers, 46 chairs (accommodating up to 60 people), and a total length of 640 meters, transporting up to 450 people per hour. The upper station stands at 1,050 meters and the lower one at 770 meters. At the summit, the panoramic cafeteria can host 80 people and features two terraces rising 20 meters high. In the winter, the chairlift runs until 6:00 p.m.; in summer, until 7:30 p.m. thanks to extended daylight. After descending, you’ll have the chance to browse a wide selection of artisanal local products—from textiles and woodwork to candles, ceramics, and cosmetics—which make this scenic walk a highlight not to be missed. 


Cerro Campanario is known as the “center of the landscape” and truly elevates visitors to the “right height of astonishment,” making it one of Bariloche’s iconic experiences.


Guide: Included for the day

Meals: Breakfast

Accommodation:

  • Mid-Range: Hotel Carlos V Patagonia Bariloche.
Day 13

place Bariloche: Enjoy a Leisure Day

Spend the day in Bariloche as you wish. Discover chocolaterias, hike mountain trails, or join an optional sightseeing excursion in this alpine town on the shores of Lake Nahuel Huapi. 


Founded by Swiss and German immigrants, Bariloche is famed for its chocolate and Alpine-inspired architecture.


Meals: Breakfast

Accommodation:

  • Mid-Range: Hotel Carlos V Patagonia Bariloche.
Day 14

place Bariloche to Buenos Aires: Return to the Capital

Transfer to the airport for your flight to Buenos Aires. Upon arrival, head back to the ibis Buenos Aires Obelisco and enjoy the rest of the day at leisure. 


Relive the city’s lively nights or unwind after your Patagonian journey through city streets lined with jacarandas and classic cafés.


Meals: Breakfast

Accommodation:

  • Mid-Range: ibis Buenos Aires Obelisco
Day 15

place Goodbye Argentina: Departure

After breakfast, it’s time to bid farewell to Argentina. You’ll transfer from your hotel to Buenos Aires' Ezeiza International Airport (EZE) for your departure flight. Reflect on the countless wonders you’ve experienced across Patagonia—from vibrant Buenos Aires and remote Ushuaia to the glittering lakes of Bariloche. As you journey home, you’ll carry with you lasting memories of Argentina and Chile’s wild beauty, warm hospitality, and unforgettable landscapes. 


Buenos Aires’ Ezeiza Airport, the nation’s busiest international gateway since 1949, serves as the final chapter to your Patagonian adventure.


Meals: Breakfast

What’s Included

Accommodation expand_less

  • ibis Buenos Aires Obelisco
  • Hotel Boutique Casa Kalfu
  • Patagonia Jarke
  • Michelangelo Hotel Calafate
  • Hotel Carlos V Patagonia Bariloche.
  • If Patagonia Hotel

Meals expand_less

  • Breakfast (14)

Transport expand_less

  • Airport transfers at each destination (arrival and departure)
  • Transfers to and from bus stations
  • Bus ticket from Calafate to Puerto Natales
  • Bus ticket from Puerto Natales to Punta Arenas
  • Lake crossing from Puerto Varas to Bariloche

Activities expand_less

  • Sightseeing tours with local guides in small groups
  • Boat ride at Perito Moreno Glacier
  • All tours mentioned in the itinerary

Extras expand_less

  • Optional tours available (upon request)
  • Meals as specified in the itinerary

Not Included expand_less

  • International and domestic flights
  • National park entrance fees and Cuevas de Milodon entrance ticket
  • Personal expenses
  • Meals not specified in the itinerary
  • Travel Insurance

About Maria Constance

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Expertise: 

Meet local people

Rural home stays

Indigenous culture

Culture & History

Purposeful Travel

Nature & Wildlife

Water & Coastline

After my degree in tourism (2000) I went to Europe to experience new adventures. Always working in the tourism industry. Once I return, we start our own project, our travel agency, offering since 2015 our experience and knowledge to personalize trips

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